法国国家健康与医学研究院（INSERM）2022年招聘博士后（生物医学）

法国国家健康与医学研究院（法文为：Institut national de la santé et de la recherche médicale），简称“Inserm”，成立于1964年，是一所总部位于法国巴黎的国家级公共科学和技术研究机构，其前身是成立于1941年的法国国家卫生研究院，由法国卫生部和研究部共同管理。Inserm是法国唯一一个完全致力于人类健康的公共研究组织，参与从研究到治疗的全过程，其宗旨通过增进对生命和疾病的知识、创新治疗方法和公共卫生研究，促进全人类健康。

A Postdoctoral Researcher

Universities and Institutes of France

Organisation/Company: INSERM U1064 Team 2

Research Field: Biological sciences › Biology Medical sciences › Medicine

Researcher Profile: First Stage Researcher (R1)

Application Deadline: 11/12/2022 12:00 - Europe/London

Location: France › Nantes

Type Of Contract: Temporary

Job Status: Full-time

Hours Per Week: 37,5

Offer Starting Date: 09/01/2023

Eu Research Framework Programme: H2020

Under the responsibility of Carole Guillonneau, Ignacio Anegon and SéverineBézie of team 2 of the Center for Translational Research in Transplantation and Immunology INSERM 1064 in Nantes, the post-doctoral fellow will be in charge of in silico transcriptomic and proteomic characterization activities of cells regulators and improvement of their suppressive potential (by refining the method of isolation, genetic modification or targeted biochemical action) with a view to their use in cell therapy.

Main activities

Activity 1:

- Conduct, by adapting the experimental conditions, a set of techniques (transcriptomics (CITEseq), proteomics (flow cytometry), T cell culture, modification of expression of genes (CRISPR/Cas, lentivirus), proof of in vitro mechanisms in tests of co-culture)

- Bioinformatics analyzes of datasets generated by CITEsequencing or cytometry spectral for its UMR 1064 A postdoctoral researcher in Health

- Exploit and present the results of the analyses, guarantee their follow-up and quality, write experience or study reports, technical notes

Activity 2 :

- Be responsible for the proper functioning of the laboratory: purchase, supply, ensure the application of health and safety principles and rules, participate constructively in lab meetings and lab life in general

- Participate in the writing of publications, technical and scientific presentations, attend scientific congresses

Offer Requirements Skills/Qualifications

General, theoretical or disciplinary knowledge:

- Applied IT (Seurat R package, scRepertoire package)

- Cell Biology and Immunology (in-depth knowledge)

- Health and safety regulations

- Written and oral English language

Operational skills:

- Design experimental devices

- Write scientific papers

- Implement biology techniques (library generation for sequencing (Chromium Next GEM), autonomy in multi-color flow cytometry, cell sorting, culture cell, proliferation test)

- Use activity-specific software (Seurat R package, scRepertoire package, Software Flowjo, GraphPad prism

know-how :

- Ability to analyze and interpret data

- Rigor, writing and synthesis ability, communication with all types of interlocutors (technical or not)

- Motivation for research

Specific Requirements

A PhD in immunology and bioinformatic skills.

Contact Information

Organisation/Company: INSERM U1064 Team 2

Organisation Type: Public Research Institution

Website: https:// www. itun.nantes.inserm.fr/index.php/team-2/guillonneaus-group/

Country: France

City: Nantes

Street: 30 Bd Jean Monnet

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